This traditional legal effort is paired with an aggressive social-media operation run by two men, Russ Greene and Russell Berger. At CrossFit headquarters in Santa Cruz, they are known as the Russes.The Russes assist the company's conventional corporate social-media efforts (running the Twitter handle, promoting company news on the CrossFit Facebook page) while also closely monitoring what they call "the wide world of Internet assholes": chronic complainers, trolls, Wikipedia page editors, cynical bloggers, even the American College of Sports Medicine, which the Russes and Glassman believe has it in for CrossFit. When the Russes feel any of these parties go over the line, their approach is simple: They obliterate them. (See "Social Media, CrossFit Style.")
One larger randomized controlled trial followed 70 post-menopausal Swedish women with obesity for two years, who were placed on either a Paleo diet or a Nordic Nutrition Recommendations (NNR) diet.  The Paleo diet provided 30% of total calories from protein, 40% fat (from mostly monounsaturated and polyunsaturated fats) and 30% carbohydrates. It included lean meats, fish, eggs, vegetables, fruits, berries, nuts, avocado, and olive oil. The NNR diet provided less protein and fat but more carbohydrate with 15% protein, 25-30% fat, and 55-60% carbohydrates, including foods similar to the Paleo diet but also low-fat dairy products and high-fiber grains. Both groups significantly decreased fat mass and weight circumference at 6 and 24 months, with the Paleo diet producing greater fat loss at 6 months but not at 24 months. Triglyceride levels decreased more significantly with the Paleo diet at 6 and 24 months than the NNR diet.
And she has a point: Many of the foods on the "no" list have nutritional benefits and can be a smart addition to a healthy diet. "Whole grains, beans and yogurt are really important for our gut health, yet on this diet, they are not allowed," says Brooke Zigler, RD. "By eliminating these food groups, people could be missing out on key nutrients in their diet."
Transformed cells adapt metabolism to support tumor initiation and progression. Specific metabolic activities can participate directly in the process of transformation or support the biological processes that enable tumor growth. Exploiting cancer metabolism for clinical benefit requires defining the pathways that are limiting for cancer progression and understanding the context specificity of metabolic preferences and liabilities in malignant cells. Progress toward answering these questions is providing new insight into cancer biology and can guide the more effective targeting of metabolism to help patients.