Downsides: Prepare for a bit of a rise in grocery cost. Prepared foods cost less than whole foods. This is American governmental ag subsidies in a nutshell. It's unfortunate and unfair, but true. Also, as others have mentioned, you will be in the kitchen more. Again, it helps if one of you cooks and the other cleans up. It's a little annoying to be sure, but the results are more than worth the annoyances. It is also very difficult to eat out. You pretty much are limited to places that are expensive and accommodating, delis where you know and trust the ingredients, or Chipotle. Again, the slight isolation (if you can do this or at least begin it when you have a little time to spare and don't have a lot of socializing) helped.
Trying to introduce dairy back into my diet hurt my stomach and would send me into a sneezing fit. In this way, the Whole30 worked as a type of elimination diet for me, without which I may have never realized that dairy isn't my friend. I'll still suffer the consequences if I cross paths with a cheese plate at a work event, but I've made the permanent switch to tofu cream cheese and coconut milk — alternatives I would've never touched before Whole30 that are actually delicious.
Dr. Uffe Ravnskov reviews the ongoing statins debate by comparing his recent publication, “LDL-C does not cause cardiovascular disease,” and the pro-statin claims of the editors of Circulation and the Cholesterol Treatment Trialists’ (CTT) Collaboration. He (along with Drs. Zoë Harcombe and Malcolm Kendrick) notes critical errors and obfuscation in the CTT’s recent Lancet meta-analysis and observes that the published data on coronary mortality, serious adverse events, and statin side effects is misrepresented, not statistically significant, or not provided for further analysis.