A great question to ask is “Does the Paleo diet work?” Here we have a head to head comparison between the Paleo diet and Mediterranean diet in insulin resistant Type 2 Diabetics. The results? The Paleo diet group REVERSED the signs and symptoms of insulin resistant, Type 2 diabetes. The Mediterranean diet showed little if any improvements. It is worth noting that the Mediterranean diet is generally held up by our government as “the diet to emulate” despite better alternatives. You can find an abstract and the complete paper here.

It takes 30 days to push the reset button on your health and change your relationship with food. This is the concept behind Melissa and Dallas Hartwig’s Whole30 program. By eating non-processed whole foods and ditching grains, dairy, and sugar, you will reduce inflammation in your system, clear up your skin, and revitalize your energy stores. These are just a few of the benefits this program boasts.
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This one was hard for us to grasp, so it deserves some explanation. If a Paleo pancake calls for nothing but Whole30-approved ingredients (eggs and bananas), the flapjack is still off-limits. The Whole30 wants you to change your habits and your emotional relationship with food. "Your brain doesn't know the difference between an almond flour brownie and your mom's recipe; it just knows you crave sugar. So if you keep eating those sweets during the 30 days, your habits aren't changing," Hartwig says. Don't shoot the messenger!
Former athletes – CrossFit has built-in teamwork, camaraderie, and competition. Almost all workouts have a time component to them, where you either have to finish a certain number of repetitions of exercises in a certain amount of time, or the time is fixed and you need to see how many repetitions you can do of an exercise. You get to compete with people in your class, and go online to see how you did against the world’s elite CrossFit athletes. There is even an international competition for those that become truly dedicated.

There will be two Opens in 2019. Our first Open of the year just kicked off on February 21st, and will run will 5 weeks. This if Open will be a similar structure to the one we’re used to. The other Open will be in October. The October Open will help determine the athletes participating in the 2020 games. From then on, the Open will be in October only. As of right now, we have no insight as to what the October Open will look like or when the 2020 Games will take place. 
It was in Glassman's own divorce case, though, that the CrossFit defense arsenal launched its full firepower. Lauren and Greg's marriage hit the rocks in 2009. Lauren became pregnant with twins and could no longer travel to the seminars.Greg, wrapped up with CrossFit, became more and more distant. Rumors of infidelity swirled. Soon the two were living in separate houses. In March 2010, Lauren officially filed for divorce. But the case didn't come to a head until July 2012, when Lauren filed a motion to sell her 50 percent stake in the company to Anthos Capital, a Menlo Park, California-based venture capital firm, for $20 million. Glassman, and in short order CrossFit, hit the ceiling.
Interestingly, all of these seemingly unrelated diseases share a common cause: damage to the intestinal lining which allows large, undigested food particles to make their way into the body. This is called “leaky gut and the autoimmune response”. Here is a 7-part video series by Prof. Loren Cordain describing the etiology of Multiple Sclerosis. And please watch this TED talk by Dr. Terry Wahls, MD as she describes how she reversed her Multiple Sclerosis with a paleo diet. If you have an autoimmune disease you might consider trying the autoimmune protocol of the paleo diet. If you do, please tell us about your experience.
When the clock struck midnight, I couldn't wait any longer: I helped myself to a serving of plain white rice. I sat on my couch cross-legged, eating each spoonful with my eyes closed like one of the yogurt commercial ladies. I even smiled. The next day, I ate more gluten-free carbs, like rice and paleo pancakes. I also had wine and tequila, a grain-free liquor option. I didn't get bombed like I was worried about, but I did have a worse-than-usual hangover the next day. The fun night out was worth it, though.
Still, it was a tad depressing to watch my boyfriend eat whatever he wanted while I was on the sideline sipping tea. "I miss sharing food memories with you," he said at one point. Sigh. So the next day, we headed to a local brunch spot, and I ordered a Whole30–compliant dish from the menu. I got a bunless burger topped with a fried egg, avocado, lettuce, tomato, and onion plus a side salad instead of fries. Let me tell you, this bunless burger tasted like the juiciest thing I'd eaten in my entire life. After nearly two weeks of cooking every meal, it was nice to have someone else do it for me.

By the end of my first Whole30, I had an entire document full of recipes I still wanted to try, which motivated me to keep going. Yes, you can stay compliant by eating steamed chicken and lettuce every day, but why would you do that to yourself? "Find foods that are easy to make and that you enjoy eating," Cohn says. "If you eat foods that you don’t like just to follow the diet, you are not going to continue to eat those foods once you are done with the 30 days." Pro tip: Google the Whole30 version of your favorite meal, there's probably a recipe out there for it. (Unless that meal is cake.) This really helped reignite my love for cooking and encouraged me to continue preparing my own meals, instead of relying on Seamless delivery.
One of the most interesting experiments comes after you finish Whole30 and slowly start adding foods back into your diet. You get to test how foods you stopped eating during the month affected you after you added them back in. The most shocking for me? Legumes make me feel bloated (they just do!). When I added gluten back, the next day I broke out in a rash. And now that I've curbed my "sugar dragon" (that's what they call sugar cravings on Whole30), I try to avoid sugar as much as humanly possible. In fact, December came after my Whole30 experience, so of course I indulged in a few glasses of wine at a holiday party, and BOOM — my skin broke out. Now I have a better idea of what to avoid altogether, and what to watch if I do decide to indulge.
If you have been in a state of dependency on food--be it sugars, alcohol, chips, ice cream, just about anything--or if you have been unwell, unsuited to the world physically or emotionally--or, if you simply feel blah and would like to lose a little bit of weight--please consider trying this program. You might think, "I don't eat that badly! I eat a lot of whole foods!" which is what most people think of themselves (I sure did). But when you actually make a conscious decision to eliminate foods from your diet, you will see that even the small amounts of crap that you've been eating regularly matter. Prepare to be amazed. I sound like an evangelical, I know. It's a little embarrassing. But it is all true.

Between 2009 and 2018, competitors qualified for the Games through participation at CrossFit Games regional events. For the 2019 Games, CrossFit, Inc. discontinued hosting the Regional qualifier and instead sanctioned independent fitness events as qualifiers separate from the Open. Most of the sanctioned events were already widely participated in by CrossFit Games athletes, often used as a part of off-season training, around the world. Each sanctioned event has its own rules for participation, but athletes that attend the sanctioned events are either by invite or through the event's qualification process.

Transformed cells adapt metabolism to support tumor initiation and progression. Specific metabolic activities can participate directly in the process of transformation or support the biological processes that enable tumor growth. Exploiting cancer metabolism for clinical benefit requires defining the pathways that are limiting for cancer progression and understanding the context specificity of metabolic preferences and liabilities in malignant cells. Progress toward answering these questions is providing new insight into cancer biology and can guide the more effective targeting of metabolism to help patients.

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