One of the most interesting experiments comes after you finish Whole30 and slowly start adding foods back into your diet. You get to test how foods you stopped eating during the month affected you after you added them back in. The most shocking for me? Legumes make me feel bloated (they just do!). When I added gluten back, the next day I broke out in a rash. And now that I've curbed my "sugar dragon" (that's what they call sugar cravings on Whole30), I try to avoid sugar as much as humanly possible. In fact, December came after my Whole30 experience, so of course I indulged in a few glasses of wine at a holiday party, and BOOM — my skin broke out. Now I have a better idea of what to avoid altogether, and what to watch if I do decide to indulge.
The WHO trial (so named because the international team of principal investigators contained World Health Organization members) tested the potential of clofibrate, a “pre-statin” cholesterol-lowering agent, to reduce heart attack morbidity and mortality. The investigators ultimately concluded that clofibrate "cannot be recommended as a lipid-lowering drug for community-wide primary prevention of ischaemic heart disease.” Nevertheless, clofibrate remained in use until 2002, when it was pulled for increasing cancer rates. In their review of studies such as the WHO trial, Uffe Ravnskov and David Diamond observe, “Despite the largely disappointing findings from 50 years of cholesterol lower[ing] trials, the indictment and conviction of cholesterol as the causal agent in CVD [cardiovascular disease] has stood the test of time. … [Yet] the grand effort to reduce cholesterol as a strategy to improve health has failed.”