The Paleo diet is the healthiest way you can eat because it is the ONLY nutritional approach that works with your genetics to help you stay lean, strong and energetic! Research in biology, biochemistry, Ophthalmology, Dermatology and many other disciplines indicate it is our modern diet, full of refined foods, trans fats and sugar, that is at the root of degenerative diseases such as obesity, cancer, diabetes, heart disease, Parkinson’s, Alzheimer’s, depression and infertility. – Robb Wolf
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The Primal Blueprint: Reprogram your genes for effortless weight loss, vibrant health, and boundless energy by Mark Sisson is a journey through human evolution, comparing the life and robust health of our hunter-gatherer ancestors with a day in the life of a modern family. The author offers a solution in 10 empowering Blueprint Lifestyle Laws: eat lots of plants and animals, avoid poisonous things, move frequently at a slow pace, lift heavy things, sprint once in a while, get adequate sleep, play, get adequate sunlight, avoid stupid mistakes, and use your brain. The reader learns how the right high-fat diet can actually help one lose weight and how popular low-fat, grain-based diets might trigger illness, disease, and lifelong weight gain. The author presents a comprehensive, well thought out paleo style eating plan in a humorous and organized manner. He backs up all his work with research, natural wisdom, and historical timelines. He disputes the role of dietary saturated fat in causation of arteriosclerosis, the role of cholesterol in promotion of heart disease, and the costly over-promotion of expensive, potentially toxic statin drugs. He criticizes our massive overeating of refined carbohydrates and urges avoidance of grains, cereals, bread and sugar. There is specific recommendation for "primal" food including more natural healthy fats and meats, fruits, veggies, and nuts. Some reviewers consider this to be the best of the various paleo books. The many Amazon reviews average to 5 stars. The author's popular and worthwhile web site: Mark's Daily Apple. The 2nd Edition was published January 14, 2012.
The Sugar Addict's Total Recovery Program by Kathleen DesMaisons. While this isn't really a paleo book, it does point out issues with the foods we aren't eating. The books claims the excessive processed sugar consumed is responsible for "mood swings, depression, fatigue, fuzzy thinking, PMS, impulsivity ... [and] unpredictable temper." She says her research shows indulging in sugar highs should be treated much more seriously, akin to heroin or alcohol dependency, because sugar causes spikes in the neurotransmitters serotonin and beta-dopamine just like those drugs.
The Vegetarian Myth: Food, Justice, and Sustainability by Lierre Keith is against industrial farming. She spent 20 years as a vegan, and now reveals the risks of a vegan diet, and explains why animals belong on ecologically sound farms. And as all the neolithic foods we avoid are produced on industrial farms, she is against the foods we avoid. Here's a well thought out review by Eric Wargo: Clubbing Vegetarians Over the Head With the Truth.
This one was hard for us to grasp, so it deserves some explanation. If a Paleo pancake calls for nothing but Whole30-approved ingredients (eggs and bananas), the flapjack is still off-limits. The Whole30 wants you to change your habits and your emotional relationship with food. "Your brain doesn't know the difference between an almond flour brownie and your mom's recipe; it just knows you crave sugar. So if you keep eating those sweets during the 30 days, your habits aren't changing," Hartwig says. Don't shoot the messenger!
The other highlight recipes for me: Shakshuka (pg. 25), Beef and Sweet Potato Chili (pg. 33)—we ate that all week for lunch, Slow-Cooker Italian Beef Roast (pg 43)—use later for other meals like Poached Eggs with Salsa Verde (pg. 44), Mediterranean Bison Burger (pg. 53), Slow-Cooked Moroccan Spices Shredded Beef (pg. 61), Thai Beef Curry with Green Beans (pg. 77), Pork Posole with Tostones (pg. 87), Chipotle BBQ Chicken Thighs (pg. 128), Grilled Jamaican Jerk Salmon (pg. 192), Mexican Salmon Cakes (pg 198), Dukkah-Crusted Brussel Sprouts (pg. 224).
There are about half a dozen diets that are very similar. They all recommend you eat "meat and veg" The reason Whole 30 works for me is because you can have potatoes and fruit. An example of a whole 30 meal would be: 2 pork chops, mashed potatoes made with chicken stock, green beans, finish with your choice of fruit. My favorite is a few grapes or pineapple chunks. Also the goal it to make it 30 days without cheating. There have been several times I would think: OK I can't cheat now I only have __ more days to go. Having an end in site helped me. When I started adding back in food groups after the 30 days. I figured out that I do not do well with Dairy. Now the only dairy I use is real butter. I never thought I could live without cheese... But now I don't think it's a good idea for me. So it helps you figure out what you can and can not eat and still feel good.
Grass-fed meat is recommended on the paleo diet because it is leaner than meat from grain-fed animals and has more omega-3 fatty acids, the healthy fats that reduce inflammation in the body and protect your heart. A typical American diet is high in saturated and trans fats and lower in healthy poly- and monounsaturated fats, hence the paleo diet's emphasis on grass-fed meats.

For most people the fact the Paleo diet delivers the best results is all they need. Improved blood lipids, weight loss, and reduced pain from autoimmunity is proof enough.  Many people however are not satisfied with blindly following any recommendations, be they nutrition or exercise related. Some folks like to know WHY they are doing something. Fortunately, the Paleo diet has stood not only the test of time, but also the rigors of scientific scrutiny.
Transformed cells adapt metabolism to support tumor initiation and progression. Specific metabolic activities can participate directly in the process of transformation or support the biological processes that enable tumor growth. Exploiting cancer metabolism for clinical benefit requires defining the pathways that are limiting for cancer progression and understanding the context specificity of metabolic preferences and liabilities in malignant cells. Progress toward answering these questions is providing new insight into cancer biology and can guide the more effective targeting of metabolism to help patients.
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