For your body to enter ketosis, a good percentage of your calories (generally, somewhere between 60-80%, according to keto experts) needs to come from fats (this is why people frequently associate the Keto Diet with foods like bacon, even though most nutritionists say it's better to eat healthier items like avocados, nuts and seeds, eggs, and lean meats). The idea is that all of that fat-burning will help you lose weight, says Kizer.
The WHO trial (so named because the international team of principal investigators contained World Health Organization members) tested the potential of clofibrate, a “pre-statin” cholesterol-lowering agent, to reduce heart attack morbidity and mortality. The investigators ultimately concluded that clofibrate "cannot be recommended as a lipid-lowering drug for community-wide primary prevention of ischaemic heart disease.” Nevertheless, clofibrate remained in use until 2002, when it was pulled for increasing cancer rates. In their review of studies such as the WHO trial, Uffe Ravnskov and David Diamond observe, “Despite the largely disappointing findings from 50 years of cholesterol lower[ing] trials, the indictment and conviction of cholesterol as the causal agent in CVD [cardiovascular disease] has stood the test of time. … [Yet] the grand effort to reduce cholesterol as a strategy to improve health has failed.”