Transformed cells adapt metabolism to support tumor initiation and progression. Specific metabolic activities can participate directly in the process of transformation or support the biological processes that enable tumor growth. Exploiting cancer metabolism for clinical benefit requires defining the pathways that are limiting for cancer progression and understanding the context specificity of metabolic preferences and liabilities in malignant cells. Progress toward answering these questions is providing new insight into cancer biology and can guide the more effective targeting of metabolism to help patients.
CrossFit programming is decentralized, but its general methodology is used by thousands of private affiliated gyms, fire departments, law-enforcement agencies, and military organizations, including the Royal Danish Life Guards, as well as by some U.S. and Canadian high-school physical-education teachers, high-school and college sports teams, and the Miami Marlins.
This is a list of paleo diet meats allowed on the diet. Almost all meats are paleo by definition. Of course, you’ll want to stay away from highly processed meats and meats that are very high in fat (stuff like spam, hot dogs, and other low-quality meats), but if it used to moo, oink, or make some other sound, it’s almost certainly paleo (and, yes, that means you can still have bacon). Here’s the full list of paleo diet meats.
And if you have an iPhone or iPad, go download my Webby Award-winning app! With over 100 Whole30-approved recipes, interactive guides, a customizable shopping list, fully-emailable recipes, and a 30-day Whole30 meal plan, this app is an invaluable tool for Paleo foodies and culinary newbies alike. There’s even a dedicated Whole30 recipe category in the app!
The following links tend towards news reports of scientific studies that point out some positive aspect of the paleo diet. If you are looking for current news reports, I suggest signing up for Google Alerts for the Type: News. I have three set up, for: "caveman diet," "paleo diet," and "paleolithic diet." You can also set them up for blogs and/or websites.
CrossFit, Inc. has also been criticized for having a "cavalier" attitude towards rhabdomyolysis by promoting a character known as "Uncle Rhabdo" (a cartoon clown dying in a dramatic fashion—hooked up to a dialysis machine, with his kidneys and intestines falling on the floor). In response to this criticism, Greg Glassman stated "We introduced (Uncle) Rhabdo because we're honest and believe that full disclosure of risk is the only ethical thing to do."
Paleo Comfort Foods: Homestyle Cooking in a Gluten-Free Kitchen by Julie Sullivan Mayfield and Charles Mayfield. Implementing paleo guidelines and principles in this book (no grains, no gluten, no legumes, no dairy), the Mayfields give you 100+ recipes and full color photos with entertaining stories throughout. The recipes in Paleo Comfort Foods can help individuals and families alike lose weight, eat healthy and achieve optimum fitness, making this way of eating sustainable, tasty and fun. The many reviews at Amazon are basically flawless. The sole complaint is over the lack of nutritional information. But there is no counting on the paleo diet and its inclusion would have been inappropriate. Published September 10, 2011.
In my first CrossFit experience three years ago, I almost made myself puke because I wanted so badly to finish with a good time. Last year, I did another CrossFit workout that I hadn’t properly prepared for and cranked out 100 pull ups quickly…and I ended up walking around with T-rex arms for a WEEK because I physically could not straighten them. Not kidding.
A metaresearch group at Tilburg University in the Netherlands investigates scientists’ research methods and operations, scrutinizing questionable practices such as selective reporting of statistical tests and data massaging. The group instead advocates for practices such as preregistering studies and making experimental data immediately available for open external review and verification. Its members are optimistic that “the perverse incentives of careerist academia, to hoard data and sacrifice rigor for headline-generating findings, will ultimately be fixed.”