As of 2016 there are limited data on the metabolic effects on humans eating a paleo diet, but the data are based on clinical trials that have been too small to have a statistical significance sufficient to allow the drawing of generalizations.[3][6][20][not in citation given] These preliminary trials have found that participants eating a paleo nutrition pattern had better measures of cardiovascular and metabolic health than people eating a standard diet,[3][9] though the evidence is not strong enough to recommend the paleo diet for treatment of metabolic syndrome.[9] As of 2014 there was no evidence the paleo diet is effective in treating inflammatory bowel disease.[21]

Update: So today is day 18 on my Whole30 journey. I just wanted to let you guys know that there is a lot of cooking involved with this program. I'm actually tired of cooking, which is why I started making large meals to freeze for the week. It actually works out well for me, especially since I don't mind eating the same food everyday. I've also been drinking a lot of tea and water. I feel like it is helping to flush out more toxins from my body. I has been approximately four days since my previous review and I lost an additional 2 pounds on this journey. I have so much energy that I actually am unable to sit still like I used to. I guess I was depressed before going on this journey so the Whole30 has actually improved my mood as well. I go for a walk every day and I've actually started a new workout program!
A metaresearch group at Tilburg University in the Netherlands investigates scientists’ research methods and operations, scrutinizing questionable practices such as selective reporting of statistical tests and data massaging. The group instead advocates for practices such as preregistering studies and making experimental data immediately available for open external review and verification. Its members are optimistic that “the perverse incentives of careerist academia, to hoard data and sacrifice rigor for headline-generating findings, will ultimately be fixed.”