Two years ago, I dropped 30 pounds (and kept it off) by doing the Whole30 and continuing to eat well in the months that followed. During the 30 days on the program, I lost 11 pounds. And for me, completing it helped me form healthy habits (like reading labels and not smothering everything in cheese), taught me how to cook an arsenal of healthy recipes I actually enjoyed eating and most importantly (and the reason why I do it every January), showed me how incredible my body feels when I'm not pumping it full of sugar and alcohol. These lessons stuck with me well past the 30 days, allowing me to drop an additional 19 pounds by April of that year and finally reach my goal weight.
The WHO trial (so named because the international team of principal investigators contained World Health Organization members) tested the potential of clofibrate, a “pre-statin” cholesterol-lowering agent, to reduce heart attack morbidity and mortality. The investigators ultimately concluded that clofibrate "cannot be recommended as a lipid-lowering drug for community-wide primary prevention of ischaemic heart disease.” Nevertheless, clofibrate remained in use until 2002, when it was pulled for increasing cancer rates. In their review of studies such as the WHO trial, Uffe Ravnskov and David Diamond observe, “Despite the largely disappointing findings from 50 years of cholesterol lower[ing] trials, the indictment and conviction of cholesterol as the causal agent in CVD [cardiovascular disease] has stood the test of time. … [Yet] the grand effort to reduce cholesterol as a strategy to improve health has failed.”