Interest and participation in the event continued to grow, and in 2010, the qualification was adjusted to include hosting multiple Sectionals, a series of events open to all athletes in order to qualify for the one of the 17 Regionals. The 17 regions had Canada and the United States divided into 12 regions, with the remaining regions roughly corresponding the five other populated continents. The attendance at the Games also outgrew the ranch in Aromas and moved the Home Depot Center (later called the StubHub Center) in Carson, California. The Games also expanded the Team Division to groups of six athletes and added a Masters Division for individual men and women 55-years-old and up.
Gluten is a protein found in things like rye, wheat, and barley. It’s now being said that much of our population may be gluten-intolerant (hence all the new “gluten-free!” items popping up everywhere). Over time, those who are gluten intolerant can develop a dismal array of medical conditions from consuming gluten: dermatitis, joint pain, reproductive problems, acid reflux, and more.
Workout 4A & 4B has an 11 min time cap. It is a chipper that begins with the athlete standing tall behind their measured handstand-pushup box. At the start of the ascending clock, the athlete will kick up to a locked out handstand before performing their repetitions. They will then move onto the pull-ups and complete 50 repetitions before moving to the toes to bar to complete another 50 repetitions, and lastly onto the wall-balls, complete 50 repetitions. Athletes may take as many sets, breaking up the work as needed, to complete the required number of repetitions throughout the workout.
The Open, introduced in 2011 and so-called because participation is open to anyone, is held over five weeks in February–March; a new workout is released on each Thursday night (Pacific Time) and competitors complete the workout and submit their scores online by Monday evening, with either a video or validation by a CrossFit affiliate. Since 2013, Open workout announcements have been broadcast live, and featured two or more past CrossFit Games athletes competing head-to-head immediately following the workout description. Beginning with the 2019 Games, the top athlete from each country and the top 20 overall Open finishers qualify directly to the Games. The Open is also used for seeding purposes at the Games even if an athlete qualified through the sanctioned events; if an athlete qualifies through a sanctioned event but does not do the Open, they will be seeded at the bottom.
The Primal Blueprint Cookbook: Primal, Low Carb, Paleo, Grain-Free, Dairy-Free and Gluten-Free by Mark Sisson and Jennifer Meier. Recipes include: Roasted Leg of Lamb with Herbs and Garlic, Salmon Chowder with Coconut Milk, Tomatoes Stuffed with Ground Bison and Eggs, and Baked Chocolate Custard. Recipes are simple and have limited ingredients. Complaints are the book is stuffed with unnecessary photos and proofreading could have been better, e.g. oven temperatures were left out. And recipes are not truly paleo. Despite what is on the cover dairy is used in some recipes. The Amazon reviews average to 4+ stars.
The other highlight recipes for me: Shakshuka (pg. 25), Beef and Sweet Potato Chili (pg. 33)—we ate that all week for lunch, Slow-Cooker Italian Beef Roast (pg 43)—use later for other meals like Poached Eggs with Salsa Verde (pg. 44), Mediterranean Bison Burger (pg. 53), Slow-Cooked Moroccan Spices Shredded Beef (pg. 61), Thai Beef Curry with Green Beans (pg. 77), Pork Posole with Tostones (pg. 87), Chipotle BBQ Chicken Thighs (pg. 128), Grilled Jamaican Jerk Salmon (pg. 192), Mexican Salmon Cakes (pg 198), Dukkah-Crusted Brussel Sprouts (pg. 224).
Transformed cells adapt metabolism to support tumor initiation and progression. Specific metabolic activities can participate directly in the process of transformation or support the biological processes that enable tumor growth. Exploiting cancer metabolism for clinical benefit requires defining the pathways that are limiting for cancer progression and understanding the context specificity of metabolic preferences and liabilities in malignant cells. Progress toward answering these questions is providing new insight into cancer biology and can guide the more effective targeting of metabolism to help patients.