The burpee box over starts with the athlete facing the box, the athlete must be square and head forward to the box. NO lateral burpees allowed. The athletes chest and thighs must touch the ground on the bottom of the burpee. The athlete may jump or step onto the box and off the box. Whether jumping or stepping, BOTH feet must make contact with the top of the box at the same time. Coming off the box, the athlete must turn around and be face forward on to the box to perform their next burpee.
The WHO trial (so named because the international team of principal investigators contained World Health Organization members) tested the potential of clofibrate, a “pre-statin” cholesterol-lowering agent, to reduce heart attack morbidity and mortality. The investigators ultimately concluded that clofibrate "cannot be recommended as a lipid-lowering drug for community-wide primary prevention of ischaemic heart disease.” Nevertheless, clofibrate remained in use until 2002, when it was pulled for increasing cancer rates. In their review of studies such as the WHO trial, Uffe Ravnskov and David Diamond observe, “Despite the largely disappointing findings from 50 years of cholesterol lower[ing] trials, the indictment and conviction of cholesterol as the causal agent in CVD [cardiovascular disease] has stood the test of time. … [Yet] the grand effort to reduce cholesterol as a strategy to improve health has failed.”
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